Adherencia a la Guía de Práctica Clínica de la OPS 2016 sobre Dengue en un hospital del norte de Perú, 2022-2023.
Adherence to the 2016 PAHO Clinical Practice Guideline on Dengue in a Hospital in Northern Peru, 2022-2023.
DOI:
https://doi.org/10.57188/Keywords:
Dengue, Adherence, Clinical Practice Guidelines, Mortality. (Source: MeSH-NLM)Abstract
Objective: Effective dengue management enhances the chances of survival. The level of adherence to the suggestions in northern Peru is uncertain. The primary aim of the study was to assess adherence to the 2016 PAHO guideline on dengue in a hospital located in northern Peru during the period from 2022 to 2023. Methodology: The study performed a cross-sectional design and exploratory analysis, reviewing 140 medical records. Fifty-four percent were from 2023; 66.43% were from women; 38,57% came from a first level healthcare center; 77.14 % had diagnosis of dengue with warning signs and 20.71% had severe dengue; 18.44% died. Results: We found at least one error in the classification of severity and/or treatment in non-hospital healthcare facilities (95 %), triage (90.23%), and uviclin/observation (58.93%). Errors in classification and inadequate hydration in the first level healthcare centers, triage, and uviclin/observation were: 40.68%/60.0%, 31.0.6%/76.6%, and 15.32%/44.14 %, respectively. Persistent errors were inadequate hydration in triage (76.69%) and urinary flow in the center (81.67 %). In a bivariate analysis, mortality was associated with age 18 years or older (p = 0.047), having a case from 2023 (p = 0.008), and having severe dengue (p<0.001). In the multivariate analysis, only severe dengue (PR: 28.13, 95% CI :9.32-84.86 p<0.001), and age 18 years or older (PR:2.97, 95%CI:1.19-7.43 p: 0.020), were associated with mortality. Conclusions: We found a high frequency of misclassification and management errors in these three scenarios, but they were not associated with higher mortality.
Downloads
References
1. Pan American Health Organization. PLISA: Health Information Platform for the Americas [Internet]. Washington (DC): PAHO; [cited 2024 Feb 12]. Available from: https://opendata.paho.org/en
2. Peru. Ministerio de Salud. Centro Nacional de Epidemiología, Prevención y Control de Enfermedades. Sala situacional de dengue [Internet]. Lima: MINSA; [cited 2024 Feb 12]. Available from: https://www.dge.gob.pe/sala-situacional-dengue/diaria/
3. World Health Organization. Dengue and severe dengue [Internet]. Geneva: WHO; [cited 2022 Aug 17]. Available from: https://www.who.int/news-room/fact-sheets/detail/dengue-and-severe-dengue
4. Pan American Health Organization. Dengue: guidelines for patient care in the Region of the Americas. 2nd ed. Washington (DC): PAHO; 2016. Available from: https://iris.paho.org/items/499a0290-7f8d-4bc8-865e-94e75eee06d5
5. Peru. Ministerio de Salud. Resolución Ministerial N.° 082-2024-MINSA: Plan de prevención y control del dengue 2024 [Internet]. Lima: MINSA; 2024 [cited 2024 Mar 26]. Available from: https://cdn.www.gob.pe/uploads/document/file/5813240/5156456-resolucion-ministerial-n-082-2024.pdf
6. Peru. Ministerio de Salud. Resolución Ministerial N.° 175-2024/MINSA: Norma Técnica de Salud para la atención integral de pacientes con dengue en el Perú [Internet]. Lima: MINSA; 2024 [cited 2024 Mar 10]. Available from: https://cdn.www.gob.pe/uploads/document/file/6007546/5323501-rm-175-2024-minsa-y-nts-211-dgiesp.pdf
7. Koonisetty KS, Aghamohammadi N, Urmi T, Yavaşoglu Sİ, Rahman MS, Nandy R, et al. Assessment of knowledge, attitudes, and practices regarding dengue among physicians: a web-based cross-sectional survey. Behav Sci (Basel). 2021;11(8):105. doi:10.3390/bs11080105
8. Laoprasopwattana K, Khantee P, Saelim K, Geater A. Mortality rates of severe dengue viral infection before and after implementation of a revised guideline for severe dengue. Pediatr Infect Dis J. 2022;41(3):211-216. doi:10.1097/INF.0000000000003411
9. León-Jiménez FE, Inga-Chero JE, Mendoza-Farro NBF, Montoya-Reátegui A, Dioses-Díaz K, Cavalcanti-Ramírez S, et al. Características y errores más frecuentes en el diagnóstico y tratamiento del dengue en un hospital del norte peruano, 2022. An Fac Med (Lima). 2023;84(2):210-212. doi:10.15381/anales.v84i2.25494
10. Rodríguez J, Lastre G, Camargo J, Fuentes G, Bermejo J, Nieto V. Adherencia de los pacientes a la guía de práctica clínica del dengue (GPC_Dengue) en una clínica de Barranquilla (Atl, Col). Cienc Innov Salud. 2015;3(2):23-30.
11. Valderrama Ardila M, Velasco M, Molina López A, Perea Ayala M, Noguera Quiñones D, Rodríguez Arenas D, et al. Evaluation of the management of pediatric patients diagnosed with dengue in a medium-complexity children’s clinic, according to the new WHO guideline. Rev Colomb Salud Libre. 2011;9:33-44.
12. Peru. Ministerio de Salud. Estadística poblacional [Internet]. Lima: MINSA; [cited 2024 Apr 18]. Available from: https://www.minsa.gob.pe/reunis/data/poblacion_estimada.asp
13. Hospital de la Amistad Perú-Corea Santa Rosa II-2 [Internet]. Piura: Gobierno del Perú; [cited 2022 Sep 23]. Available from: https://www.gob.pe/hsantarosa
14. Lake EA, Demissie BW, Gebeyehu NA, Wassie AY, Gelaw KA, Azeze GA. Knowledge, attitude and practice towards COVID-19 among health professionals in Ethiopia: a systematic review and meta-analysis. PLoS One. 2021;16(2):e0247204. doi:10.1371/journal.pone.0247204
15. Carrera-Acosta L, Salvador-Salvador S, Torre-Maraví GE. Evaluación de la adherencia de guías de práctica clínica en el Seguro Social del Perú. Rev Cuerpo Med HNAAA. 2021;14(4):430-431. doi:10.35434/rcmhnaaa.2021.144.1355
16. Dirección Regional de Salud Piura. Capacitan al personal de salud para fortalecer las intervenciones sanitarias contra el dengue [Internet]. Piura: Gobierno del Perú; 2023 [cited 2023 May 30]. Available from: https://www.gob.pe/institucion/regionpiura-diresa/noticias/752982-capacitan-al-personal-de-salud-para-fortalecer-las-intervenciones-sanitarias-contra-el-dengue
17. Dirección Subregional de Salud Morropón Huancabamba. Fortalecen capacidades de personal de salud para una mejor atención de pacientes con dengue en el Alto Piura [Internet]. Piura: Gobierno del Perú; 2023. Available from: https://www.gob.pe/institucion/regionpiura-dsrsmh/noticias/768037-fortalecen-capacidades-de-personal-de-salud-para-una-mejor-atencion-de-pacientes-con-dengue-en-el-alto-piura
18. Peru. Ministerio de Salud. Piura: médicos son capacitados para atender a pacientes afectados por dengue [Internet]. Lima: MINSA; 2024 [cited 2024 Mar 26]. Available from: https://www.gob.pe/institucion/minsa/noticias/843478-piura-medicos-son-capacitados-para-atender-a-pacientes-afectados-por-dengue
19. Dirección Regional de Salud Piura. Más de 1,200 enfermeras son capacitadas para enfrentar al dengue en la región Piura [Internet]. Piura: Gobierno del Perú; 2024 [cited 2024 Mar 26]. Available from: https://www.gob.pe/institucion/regionpiura-diresa/noticias/900660-mil-200-enfermeras-son-capacitadas-para-enfrentar-al-dengue-en-la-region-piura
20. Fondo de las Naciones Unidas para la Infancia. Síntesis metodológica n.° 8: evaluación de impacto [Internet]. Florencia: UNICEF Office of Research-Innocenti; [cited 2023 Jun 6]. Available from: https://www.unicef-irc.org/publications/pdf/MB8ES.pdf
21. Balkrishnan P, Panda PK, Pandey RM, Biswas A, Aggarwal P, Vikram NK, et al. Compliance of WHO guideline on dengue management among Indian patients: an interventional quality improvement study. J Assoc Physicians India. 2019;67(4):30-34. PMID:31299835.
22. Wharton-Smith A, Green J, Loh EC, Gorrie A, Omar SFS, Bacchus L, et al. Using clinical practice guidelines to manage dengue: a qualitative study in a Malaysian hospital. BMC Infect Dis. 2019;19(1):45. doi:10.1186/s12879-019-3680-5
23. Peru. Ministerio de Salud. Dirección de Prevención y Control de Enfermedades Metaxénicas y Zoonosis. Evaluación de adherencia a normas técnicas de salud [Internet]. Lima: MINSA; [cited 2024 Apr 15]. Available from: https://lookerstudio.google.com/u/0/reporting/695d47ab-cb34-48ee-b1dc-471925689515/page/xpKkD
24. Instituto de Evaluación de Tecnologías en Salud e Investigación. Evaluación de adherencia a la Guía de Práctica Clínica para la atención de casos de dengue en el Perú en EsSalud, al 12/03/2024 [Internet]. Lima: EsSalud; 2024 [cited 2024 Apr 15]. Available from: https://ietsi.essalud.gob.pe/wp-content/uploads/2024/03/Reporte.pdf
25. Ledesma Negreiros GC, Rodríguez Vásquez S, Valencia Hipólito JV. Características clínicas y situación epidemiológica del dengue en Perú: una revisión sistemática. Rev Cuerpo Med HNAAA. 2024;17(1). doi:10.35434/rcmhnaaa.2024.171.2409
26. Llanos-Zavalaga LF, Orellana-Vásquez AT, Aguado-Taquire HF. Evaluación inicial del sistema de referencia y contrarreferencia ambulatoria en la DIRIS Lima Norte, desde los centros materno infantiles. Rev Med Hered. 2021;32(2):91-102. doi:10.20453/rmh.v32i2.3982
27. Gobierno Regional de Piura. Dirección Regional de Salud Piura. Hospital de la Amistad Perú-Corea Santa Rosa II-2. Resolución Directoral N.° 060-2022/GOB.PIURA-DRSP-HAPCSR-II-2-DIR-UDS: conformación del equipo de referencias y contrarreferencias [Internet]. Piura: Hospital Santa Rosa; 2022 [cited 2023 Jun 6]. Available from: https://www.hsantarosa.gob.pe/PORTAL/RD_060.pdf
28. Pan American Health Organization. Declaration of Alma-Ata [Internet]. Washington (DC): PAHO; 2012 [cited 2023 May 30]. Available from: https://www.paho.org/hq/dmdocuments/2012/Alma-Ata-1978Declaracion.pdf
29. Sampaio VS, Lopes R, Ozahata MC, Nakaya HI, Sousa E, Araújo JD, et al. Thinking out of the box: revisiting health surveillance based on medical records. Antimicrob Steward Healthc Epidemiol. 2023;3(1):e185. doi:10.1017/ash.2023.451
30. Peru. Ministerio de Salud. Resolución Ministerial N.° 618-2019/MINSA: Documento técnico: Plan de implementación del Registro Nacional de Historias Clínicas Electrónicas - RENHICE [Internet]. Lima: MINSA; 2019 [cited 2025 Mar 30]. Available from: https://www.gob.pe/institucion/minsa/normas-legales/283745-618-2019-minsa
Downloads
Published
Issue
Section
License
Copyright (c) 2026 Franco E. León Jiménez, Nataly BF Mendoza-Farro, Adriana Montoya Reategui, Joel Emmanuel Inga Chero, Karim M.V. Dioses Diaz, Moisés Barranzuela Herrera, Sophia Cavalcanti Ramírez, LUZ MARIA Moyano Vidal

This work is licensed under a Creative Commons Attribution 4.0 International License.
RICSA is an open access journal distributed under the terms and conditions of Creative Commons Attribution 4.0 International license







